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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: LATS1 All Species: 20.91
Human Site: S569 Identified Species: 32.86
UniProt: O95835 Number Species: 14
    Phosphosite Substitution
    Charge Score: 0
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens O95835 NP_004681.1 1130 126870 S569 H L L H Q N P S V P P Y E S I
Chimpanzee Pan troglodytes XP_001173355 1130 126853 S569 H L L H Q N P S V P P Y E S I
Rhesus Macaque Macaca mulatta XP_001090321 809 89257 A321 P A P N T V T A V T A A H I L
Dog Lupus familis XP_534537 1097 121903 A556 Q S L R G S Q A A E P A D K T
Cat Felis silvestris
Mouse Mus musculus Q8BYR2 1129 126167 S568 H L L H Q N P S V P P Y E S V
Rat Rattus norvegicus
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001506215 1121 123969 S560 H L L H Q N P S V P P Y E P L
Chicken Gallus gallus XP_419666 1136 127431 S575 H L L H Q S P S V H P Y E T G
Frog Xenopus laevis NP_001087838 1118 125984 S564 V Y E S G L K S S K E D A A G
Zebra Danio Brachydanio rerio NP_001018346 1068 120780 P555 Q I T T S P V P V R R H K R D
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster Q9VA38 1105 122470 S558 Q S N N N N N S E I K P P S C
Honey Bee Apis mellifera XP_395146 1137 124999 S605 V N N S N N N S N S S N G G N
Nematode Worm Caenorhab. elegans Q2L6W9 476 55529
Sea Urchin Strong. purpuratus XP_795100 1199 133231 Q645 S T Q S T S T Q S S S T R S E
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae P53894 756 86927 F268 T I S N Y M Y F E R R P D L L
Red Bread Mold Neurospora crassa P38679 598 67999 T110 G N S G Q Q Q T Y G N Y L S A
Conservation
Percent
Protein Identity: 100 99.6 35.8 50.9 N.A. 92.8 N.A. N.A. 80.8 85.2 74.7 63.1 N.A. 38.6 40.2 20.7 38
Protein Similarity: 100 99.8 44.7 63.4 N.A. 96.7 N.A. N.A. 87.1 92.1 83.4 73.7 N.A. 50.2 52.6 29.6 51.9
P-Site Identity: 100 100 6.6 13.3 N.A. 93.3 N.A. N.A. 86.6 73.3 6.6 6.6 N.A. 20 13.3 0 6.6
P-Site Similarity: 100 100 26.6 33.3 N.A. 100 N.A. N.A. 93.3 86.6 13.3 26.6 N.A. 26.6 13.3 0 13.3
Percent
Protein Identity: N.A. N.A. N.A. N.A. 28 24.4
Protein Similarity: N.A. N.A. N.A. N.A. 42.3 35.5
P-Site Identity: N.A. N.A. N.A. N.A. 0 20
P-Site Similarity: N.A. N.A. N.A. N.A. 26.6 26.6
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 7 0 0 0 0 0 14 7 0 7 14 7 7 7 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 7 % C
% Asp: 0 0 0 0 0 0 0 0 0 0 0 7 14 0 7 % D
% Glu: 0 0 7 0 0 0 0 0 14 7 7 0 34 0 7 % E
% Phe: 0 0 0 0 0 0 0 7 0 0 0 0 0 0 0 % F
% Gly: 7 0 0 7 14 0 0 0 0 7 0 0 7 7 14 % G
% His: 34 0 0 34 0 0 0 0 0 7 0 7 7 0 0 % H
% Ile: 0 14 0 0 0 0 0 0 0 7 0 0 0 7 14 % I
% Lys: 0 0 0 0 0 0 7 0 0 7 7 0 7 7 0 % K
% Leu: 0 34 40 0 0 7 0 0 0 0 0 0 7 7 20 % L
% Met: 0 0 0 0 0 7 0 0 0 0 0 0 0 0 0 % M
% Asn: 0 14 14 20 14 40 14 0 7 0 7 7 0 0 7 % N
% Pro: 7 0 7 0 0 7 34 7 0 27 40 14 7 7 0 % P
% Gln: 20 0 7 0 40 7 14 7 0 0 0 0 0 0 0 % Q
% Arg: 0 0 0 7 0 0 0 0 0 14 14 0 7 7 0 % R
% Ser: 7 14 14 20 7 20 0 54 14 14 14 0 0 40 0 % S
% Thr: 7 7 7 7 14 0 14 7 0 7 0 7 0 7 7 % T
% Val: 14 0 0 0 0 7 7 0 47 0 0 0 0 0 7 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 7 0 0 7 0 7 0 7 0 0 40 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _